Dear esteemed colleagues and friends,

We welcome you all to France, and the city of Toulouse, for the 2025 Hydrocephalus World Congress, which will take place between 5-8 September 2025.

Covering a full spectrum of hydrocephalus and CSF disorders affecting both children and adults, the programme of the 2025 Hydrocephalus World Congress promises to be exciting with intriguing and controversial topics.

Be part of an outstanding scientific programme by submitting your abstract now! We look forward to receiving original scientific research from hydrocephalus and CSF disorders-related professionals, to discuss developments, controversies and arguments, new practices and technologies regarding Hydrocephalus treatment.

Submit your abstract by 30 April 2025

Thematic Topics

Submit your Abstract

 

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Hydrocephalus 2024 Meeting Abstracts are published at Fluids and Barriers of the CNS

We are delighted to announce that the abstracts presented at the Hydrocephalus 2024 Meeting, held in Nagoya, Japan, 13-16 September 2024, are now published in the Fluids and Barriers of the CNS Journal.

By submitting your abstract to the Hydrocephalus 2025 World Congress, your work can also be included in next year’s publication, provided that your abstract is accepted and presented at the congress.

Learn more

View the publication

 

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Hydrocephalus Paper of the Month 📰 

We are pleased to present this month’s interesting study, “Neutrophil extracellular trap-mediated impairment of meningeal lymphatic drainage exacerbates secondary hydrocephalus after intraventricular hemorrhage“ authored by Qiang Zhang, Yujie Chen, Yingpei Li, Zhou Feng, Liang Liang, Xiaoke Hao, Wenbo Kang, Zhaoqi Zhang, Xuyang Zhang, Rong Hu, Hua Feng and Zhi Chen.

The study investigates hydrocephalus, a significant complication that can occur following intracerebral and intraventricular hemorrhages, leading to impaired cerebrospinal fluid (CSF) circulation. The research highlights the role of brain meningeal lymphatic vessels (mLVs) as critical drainage pathways for CSF and examines how the degradation of neutrophil extracellular traps (NETs) can alleviate hydrocephalus.

The findings point to a connection between mLVs, NETs, and the development of brain injury and secondary hydrocephalus, suggesting that NETs contribute to acute injury of lymphatic endothelial cells (LECs) and lymphatic thrombosis. CX3CR1 is identified as a key molecule in this process, indicating that targeting NETs may offer a new approach to prevent the obstruction of meningeal lymphatic drainage after intraventricular hemorrhage.

This research is important as it enhances our understanding of the mechanisms underlying hydrocephalus and may lead to improved therapeutic strategies for patients suffering from cerebrospinal fluid-related disorders.

Read Full Paper

 

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Become a member of the Hydrocephalus Society!

Join a community that encourages global collaboration and knowledge sharing among professionals dedicated to hydrocephalus research and care and be part of an organisation that represents the hydrocephalus community on a global scale.

Join the Hydrocephalus Society to enjoy a plethora of benefits:

• Special Discount for the Global Hydrocephalus Congress
• Access to the Abstracts of Hydrocephalus Meetings
• Members’ directory
• Access to the “Only-Members Corner”
• On demand access to the Hydrocephalus Society Global Webinar Series (2021, 2022, 2023, 2024)
• Observerships in High-Volume Hydrocephalus Departments
• Video Minutes of Hydrocephalus Meetings
• Discount for Publications at Fluids & Barriers of the CNS Journal
• Right to Participate in the General Assembly of the Society
• Global Networking
• Meet Board Members and Participate in Society Activities
• Opportunity to Host the Hydrocephalus Meeting in Your Country

Join us! It would be our pleasure to have you on board!

Become a member!

 

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Please don’t hesitate to contact us and let us know your suggestions on how we can improve and enrich the membership benefits. Your opinion is much appreciated. Send us an email at: contact@ishcsf.com to let us know how we may better meet your needs.

 

We are pleased to present this month’s interesting paper, “Presentation, management, and outcomes of pediatric hydrocephalus in Africa:

a systematic review and meta-analysis of 12,355 patients“ authored by:

Kwadwo Darko, Mina Guirguis, Michael Farid, Pooja Venkatesh, Emmanuel Kwadwo, Osei Adjei, Nancy Abu-Bonsrah, Umaru Barrie, Brett Whittemore, Salah G Aoun, Bruno P Braga, Mabel Banson, Teddy Totimeh

📊 This recent meta-analysis provides an in-depth overview of over 10,000 cases of pediatric hydrocephalus in Africa, emphasizing shunting as the main treatment method. Post-infectious hydrocephalus was identified as the cause in over 40% of cases.

Read the Full Paper here: https://pubmed.ncbi.nlm.nih.gov/

We are pleased to present this month’s interesting study, “A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus” authored by:

Amrita K Singh, Garrett Allington, Stephen Viviano, Stephen McGee, Emre Kiziltug, Shaojie Ma, Shujuan Zhao, Kedous Y Mekbib, John P Shohfi, Phan Q Duy, Tyrone DeSpenza Jr, Charuta G Furey, Benjamin C Reeves, Hannah Smith, Andre M M Sousa, Adriana Cherskov, August Alloco, Carol Nelson-Williams, Shozeb Haider, Syed R A Rizvi, Seth L Alper, Nenad Sestan, Hermela Shimelis, Lauren K Walsh, Richard P Lifton, Andres Moreno-De-Luca, Sheng Chih Jin, Paul Kruszka, Engin Deniz and Kristopher T Kahle

This study from Harvard and Yale Universities suggests that SMARCC1 variants lead to congenital hydrocephalus by altering the epigenetic regulation of gene expression of neural progenitor cell proliferation. These findings have the potential to improve the prognosis and treatment of affected children.

Read the Full Paper here: https://pubmed.ncbi.nlm.nih.gov/38128548/

We are pleased to present this month’s interesting study, “Prediction of Surgical Outcomes in Normal Pressure Hydrocephalus by MR Elastography”, authored by Pragalv Karki, Matthew C Murphy, Petrice M Cogswell, Matthew L Senjem, Jonathan Graff-Radford, Benjamin D Elder, Avital Perry, Christopher S Graffeo, Fredic B Meyer, Clifford R Jack Jr, Richard L Ehman and John Huston 3rd.

This study uses MR Elastography to predict surgical outcomes in Normal Pressure Hydrocephalus (NPH), offering a non invasive alternative to traditional methods. Results suggest improved NPH diagnostic odds ratio and positive predictive value. This advancement could significantly improve the management of Normal Pressure Hydrocephalus, impacting the lives of those affected by this condition.

Read the Full Paper here: https://pubmed.ncbi.nlm.nih.gov/38272572/

“Ventriculoatrial Shunt Versus Ventriculoperitoneal Shunt: A Systematic Review and Meta-Analysis” authored by: Leonardo de Barros Oliveira, Fernando Hakim, Gabriel da Silva Semione, Raphael Bertani, Savio Batista, Lucca B Palavani, Marcelo Porto Sousa, Diego F Gomez-Amarillo, Isabella Mejia-Michelsen, Fernando Campos Gomes Pinto, Nicollas Nunes Rabelo, Leonardo C Welling, Eberval Gadelha Figueiredo.

Exciting findings from the latest research by the Hydrocephalus Society! A recent study compared ventriculoatrial and ventriculoperitoneal shunting techniques, revealing no significant differences in outcomes. More research, especially in adults, is needed. Emphasizing the importance of future randomized trials for optimal cerebrospinal fluid drainage. This work supports personalized neurosurgical approaches, improving decision-making in hydrocephalus treatment. Advancing strategies for managing hydrocephalus.

#HydrocephalusResearch #Neurosurgery #MedicalAdvancements 🧠✨

Read the Full Paper here: https://pubmed.ncbi.nlm.nih.gov/38117090/

“The glymphatic system for neurosurgeons: a scoping review ” authored by:

Mohammad Al Masri, Alba Corell, Isak Michaëlsson, Asgeir S. Jakola and Thomas Skoglund.

This review by the Neurosurgery department at Gothenburg, offers an insightful analysis on the impact of glymphatic system in different conditions such as Idiopathic normal pressure hydrocephalus, Idiopathic intracranial hypertension, Subarachnoid hemorrhage, Stroke, Intracranial tumors and Traumatic brain injury and its potential role as a therapeutic target.

doi: 10.1007/s10143-024-02291-6

Read more here: https://link.springer.com/article/10.1007/s10143-024-02291-6

“Prevalence of Possible Idiopathic Normal Pressure Hydrocephalus in Sweden: A Population-Based MRI Study in 791 70-year-old Participants” authored by: Clara Constantinescu, MD, Carsten Wikkelsø, MD, PhD, Eric Westman, PhD, Doerthe Ziegelitz, MD, PhD, Daniel Jaraj, MD, PhD ,Lina Rydén, MD, PhD, Ingmar Skoog, MD, PhD and Mats Tullberg, MD, PhD.

This paper by University of Gothenburg highlights the epidemiological impact of iNPH in the aging society and shows that iNPH is probably a largely underdiagnosed and undertreated disorder.

Read more here: https://www.neurology.org/doi/10.1212/WNL.0000000000208037

Dear Colleagues and Friends,

Hydrocephalus Society is delighted to invite you to register for yet another session of the Global Webinar Series 2023-2024: Adult CSF dynamics disturbances: Basics and Management.

Join us now for FREE and reserve your spot for Part 4!